Quinolones Residue Detection Service: Purpose, Methods, and Applications
Quinolones residue detection services are specialized analytical services designed to identify and quantify traces of quinolone antibiotics in food products, animal tissues, water, and environmental samples.
Quinolones are a class of broad-spectrum antibiotics widely used in veterinary medicine, aquaculture, and livestock management to treat bacterial infections. While effective in promoting animal health, residual quinolones in consumable products can pose risks to human health, including antibiotic resistance, allergic reactions, and disruption of gut microbiota.
The purpose of quinolones residue detection services is to ensure food safety, regulatory compliance, and public health protection. By monitoring and identifying residual levels in meat, poultry, fish, milk, and eggs, these services help prevent inadvertent consumption of antibiotic residues. Routine monitoring is also critical for quality assurance in the food industry and for meeting safety standards established by regulatory authorities.
Detection Methods
Detection of quinolone residues relies on sensitive and accurate analytical techniques. Common methods include:
High-Performance Liquid Chromatography (HPLC): A widely used method that separates quinolone compounds from samples and quantifies their concentration using UV or fluorescence detectors. HPLC is highly precise and suitable for routine screening of multiple quinolone compounds.
Liquid Chromatography-Mass Spectrometry (LC-MS/MS): Combines the separation capabilities of HPLC with mass spectrometry to identify and quantify quinolone residues with high sensitivity and specificity. LC-MS/MS can detect multiple antibiotics simultaneously, even at very low concentrations.
Enzyme-Linked Immunosorbent Assay (ELISA): A bioanalytical method that uses antibodies specific to quinolones to detect residues. ELISA is rapid, cost-effective, and suitable for high-throughput screening, although it may require confirmation by chromatographic methods.
Capillary Electrophoresis and Fluorescence Detection: These methods separate quinolone compounds based on charge and size, allowing precise measurement of residues in complex matrices.
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